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Anti-DAP12 Antibody
基本信息
eCl@ss | 32160702 |
General description【一般描述】 | Natural killer (NK) cells are lymphocytes that function as a component of innate immunity against intracellular and parasitic pathogens, and possibly tumors. DAP12 is expressed on the surface of NK cells as a disulfide-linked homodimer and contains an immunoreceptor tyrosine based activation motif (ITAM) in its cytoplasmic domain. DAP12 non-covalently associates with members of the killer cell immunoglobulin-like receptor (KIR) family resulting in cellular activation. |
Specificity【特异性】 | Recognizes human DAP12. This antibody detects a band of approximately 12 kDa in Western blot analysis of U937 cell lysate. |
Immunogen【免疫原】 | Synthetic peptide corresponding to amino acid residues 89-113 of human DAP12 (Accession # AAD09437). |
Application【应用】 | Anti-DAP12 Antibody is an antibody against DAP12 for use in WB. Western blot: 1.0 μg/mL Optimal working dilutions must be determined by the end user. Research Sub Category Immunoglobulins & Immunology Research Category Inflammation & Immunology |
Physical form【外形】 | Protein A purified immunoglobulin. Liquid in 0.02M Phosphate Buffer, 0.25M NaCl, with 0.1% sodium azide. Format: Purified |
Analysis Note【分析说明】 | Control Western blot positive control: U937 cell line |
Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
Legal Information【法律信息】 | CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
antibody form【抗体形式】 | purified immunoglobulin |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
species reactivity | human |
manufacturer/tradename | Chemicon® |
technique(s) | western blot: suitable |
NCBI accession no.【NCBI登记号】 | NM_003332.2 NM_198125.1 |
UniProt accession no.【UniProt登记号】 | O43914 |
shipped in【运输】 | wet ice |
Gene Information | human ... TYROBP(7305) |
产品说明
Storage and Stability【储存及稳定性】 | Maintain at 2-8°C for up to 12 months from date of receipt. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 2 |