您的位置：首页 > 产品中心 > Anti-Myosin 2 Antibody, clone 5B11.1
Anti-Myosin 2 Antibody, clone 5B11.1
产品别名
Anti-Myosin 2 Antibody, clone 5B11.1
Myosin-2, Myosin heavy chain 2, Myosin heavy chain 2a, MyHC-2a, Myosin heavy chain Iia, MyHC-Iia, Myosin heavy chain, skeletal muscle, adult 2
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Myosin is a hexameric protein consisting of two heavy chains including Myosin-2 (MYH2), two regulatory light chains, and two alkali light chains. The myosin-2 heavy chain interacts with the actin cytoskeleton and mediates muscle contractility in eukaryotic cells. Defects in myosin-2 result in inclusion body myopathy type 3. |
| Immunogen【免疫原】 | KLH-conjugated linear peptide corresponding to mouse Myosin 2. |
| Application【应用】 | Research Category Cell Structure Western Blot Analysis: 0.5 µg/mL from a representative lot detected Myosin-2 in L6 cell lysate (Myosin may be observed as a smear in some cell lysates). Western Blot Analysis: A representative lot detected Myosin-2 in mouse heart cell cytosolic extracts. Research Sub Category Cytoskeleton This Anti-Myosin 2 Antibody, clone 5B11.1 is validated for use in Western Blotting, IHC for the detection of Myosin 2. |
| Quality【质量】 | Evaluated by Immunohistochemistry in human cardiac muscle tissue. Immunohistochemistry Analysis: A 1:300 dilution of this antibody detected Myosin-2 in human cardiac muscle tissue. |
| Physical form【外形】 | Purified by Ion-Exchange Chromatography Format: Purified Purified mouse monoclonal IgG3κ in buffer containing PBS with 0.05% sodium azide. |
| Analysis Note【分析说明】 | Control Human cardiac muscle tissue |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | 5B11.1, monoclonal |
| species reactivity | mouse, human, rat |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| isotype【同位素/亚型】 | IgG3κ |
| NCBI accession no.【NCBI登记号】 | NP_060004 |
| UniProt accession no.【UniProt登记号】 | Q9UKX2 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | ~220 kDa observed |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 2 |
