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Anti-Tbr1 Antibody
| 产品编号： | 4155002 |
| 规格： | from rabbit, purified by affinity chromatography |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-Tbr1 Antibody
T-box, brain, 1, T-brain-1, T-box brain protein 1
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Tbr1 gene is a member of a conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Tbr1, a putative transcription factor known to be expressed in post-mitotic neurons, has been found highly expressed in glutamatergic early-born cortical neurons. A similar protein has been disrupted in mice and shown to be critical for early cortical development, and causes loss of projection neurons in the olfactory bulbs and olfactory cortex. The C-terminal region the Tbr1 derived protein was found to be necessary and sufficient for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase. |
| Immunogen【免疫原】 | Epitope: This antibody recognizes Tbr1 near the N-terminus. KLH-conjugated linear peptide corresponding to mouse Tbr1 near the N-terminus. |
| Application【应用】 | Immunohistochemistry Analysis: 1:400 dilution from a previous lot detected Tbr1 in mouse cerebellum tissue. Research Category Neuroscience Research Sub Category Developmental Neuroscience Anti-Tbr1 Antibody detects level of Tbr1 & has been published & validated for use in IH(P). |
| Quality【质量】 | Evaluated by Immunohistochemistry in mouse frontal cortex tissue. Immunohistochemistry Analysis: 1:400 dilution of this antibody detected Tbr1 in mouse frontal cortex tissue. |
| Physical form【外形】 | Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. Affinity purified |
| Analysis Note【分析说明】 | Control Mouse frontal cortex tissue |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | mouse, horse, pig |
| species reactivity (predicted by homology) | canine (based on 100% sequence homology), rat (based on 100% sequence homology), equine (based on 100% sequence homology), porcine (based on 100% sequence homology), bovine (based on 100% sequence homology), opossum (based on 100% sequence homology) |
| technique(s) | immunohistochemistry: suitable (paraffin) |
| NCBI accession no.【NCBI登记号】 | NP_033348 |
| UniProt accession no.【UniProt登记号】 | Q64336 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... TBR1(10716) |
产品说明
| Target description【目标描述】 | 74kDa calculated |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
