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Glutathione Monoethyl Ester-CAS 118421-50-4-Calbiochem
| 产品编号： | 4157067 |
| 规格： | Cell-permeable derivative of glutathione (GSH) that undergoes hydrolysis by intracellular esterases to release GSH. |
| CAS NO： | 118421-50-4 |
| 包装规格： | 50 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
118421-50-4
Glutathione Monoethyl Ester-CAS 118421-50-4-Calbiochem
γ-GCE, L-γ-Glutamyl-L-cysteinyl Ethyl Glycinate, GSH-MEE
基本信息
| Empirical Formula【经验(实验)分子式】 | C12H21N3O6S |
| Molecular weight | 335.38 |
| General description【一般描述】 | Cell-permeable derivative of glutathione (GSH) that undergoes hydrolysis by intracellular esterases thereby increasing intracellular GSH concentration in many tissues and cell types. Effective transport of GSH-MEE has been used to protect cells against radiation damage, oxidants and various toxic compounds including heavy metals. A protective agent against cellular damage, such as cataracts and mitochondrial degeneration. Cell-permeable derivative of glutathione (GSH) that undergoes hydrolysis by intracellular esterases to release GSH. Effective transport of GSH-MEE has been used to protect cells against damage from radiation, oxidants, and various toxic compounds including heavy metals. A protective agent against cellular damage such as in cataracts and mitochondrial degeneration. |
| Biochem/physiol Actions【生化/生理作用】 | Primary Target Effective transport of GSH-MEE Product does not compete with ATP. Reversible: no Cell permeable: no |
| Warning【警告】 | Toxicity: Standard Handling (A) |
| Reconstitution【重悬】 | Following reconstitution, aliquot and freeze (-20°C). Unstable in solution; reconstitute just prior to use. |
| Other Notes【其他说明】 | Grattagliano, I., et al. 1995. J. Pharmacol. Exp. Ther. 272, 484. Martensson, J., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 317. Anderson, M.E., and Meister, A. 1989. Anal. Biochem. 183, 16. Anderson, M.E., et al. 1985. Arch. Biochem. Biophys. 239, 538. Wellner, V.P., et al. 1984. Proc. Natl. Acad. Sci. USA 81, 4732. Puri, R.N., and Meister, A. 1983. Proc. Natl. Acad. Sci. USA 80, 5258. |
| Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | >90% (TLC) |
| form【形式】 | solid |
| manufacturer/tradename | Calbiochem® |
| storage condition【储存条件】 | OK to freeze desiccated (hygroscopic) |
| color【颜色】 | white |
| solubility【溶解性】 | water: 50 mg/mL |
| shipped in【运输】 | ambient |
| storage temp.【储存温度】 | −20℃ |
| InChI | 1S/C12H21N3O6S/c1-2-21-10(17)5-14-11(18)8(6-22)15-9(16)4-3-7(13)12(19)20/h7-8,22H,2-6,13H2,1H3,(H,14,18)(H,15,16)(H,19,20)/t7-,8-/m0/s1 |
| InChI key | JKRODHBGNBKZLE-YUMQZZPRSA-N |
| packaging【包装】 | 50 mg in Glass bottle Packaged under inert gas |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 1 |
