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Propargyl-PEG1-acid

产品编号:4168640
规格:≥95%
CAS NO:55683-37-9
包装规格:50 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
416864050 MG792
产品别名

55683-37-9

Propargyl-PEG1-acid

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C6H8O3
Molecular weight
128.13
MDL number
MFCD10689189
Application【应用】
This is a crosslinker with an alkyne group on one end and a carboxyl group on the other end. The alkyne can be used to attach to an azide using copper-catalyzed click chemistry. The compound contains a single PEG unit to help improve solubility.
Propargyl-PEG1-acid is a heterobifunctional, PEGylated crosslinker featuring a carboxylic acid at one end and propargyl group at the other for reaction with azide-containing compounds using click chemistry. The hydrophillic PEG linker facilitates solubility in biological applications. Propargyl-PEG1-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC® molecules) for targeted protein degradation.
Legal Information【法律信息】
PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license
产品性质
Assay【测定】
≥95%
form【形式】
liquid
storage temp.【储存温度】
−20℃
SMILES string
OC(CCOCC#C)=O
InChI
1S/C6H8O3/c1-2-4-9-5-3-6(7)8/h1H,3-5H2,(H,7,8)
InChI key
GMFDYXLFHSFUHE-UHFFFAOYSA-N
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 3
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