您的位置：首页 > 产品中心 > 1347760-82-0， Propargyl-PEG3-acid
Propargyl-PEG3-acid
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 4168642 | 50 MG | 1200 |
产品别名
1347760-82-0
Propargyl-PEG3-acid
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C10H16O5 |
| Molecular weight | 216.23 |
| MDL number | MFCD22201521 |
| NACRES | NA.22 |
| Application【应用】 | Propargyl-PEG3-acid is a heterobifunctional, PEGylated crosslinker featuring a carboxylic acid at one end and propargyl group at the other for reaction with azide-containing compounds using click chemistry. The hydrophillic PEG linker facilitates solubility in biological applications. Propargyl-PEG3-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC® molecules) for targeted protein degradation. This is a crosslinker with an alkyne group on one end and a carboxyl group on the other end. The alkyne can be used to attach to an azide using copper-catalyzed click chemistry. The compound contains three PEG units to help improve solubility. |
| Legal Information【法律信息】 | PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license |
产品性质
| form【形式】 | liquid |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | C#CCOCCOCCOCCC(O)=O |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
