Trovafloxacin mesylate

C₂₀H₁₅F₃N₄O₃ · CH₃SO₃H

512.46

MFCD00913361

329823684

NA.77

Trovafloxacin mesylate has been used as a test compound in toxicity assay to assess its toxicity in 2D hepatocyte cultures. It has also been used to manipulate the mechanism of apoptotic cell disassembly during apoptosis.

Trovafloxacin mesylate acts as a pannexin1 (Panx1) inhibitor.
Trovafloxacin mesylate is a broad spectrum antibiotic. Trovafloxacin mesylate blocks the activity of DNA gyrase and topoisomerase IV, enzymes essential in the repliction, transcription, and repair of bacterial DNA.

This compound was developed by Pfizer for Immunology research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.

To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Sold for research purposes under agreement from Pfizer Inc.
Pfizer is a registered trademark of Pfizer, Inc.

100

>98% (HPLC)

powder

Pfizer^®

white to off-white

DMSO: >10 mg/mL

Pfizer

room temp

CS(O)(=O)=O.NC1C2CN(CC12)c3nc4N(C=C(C(O)=O)C(=O)c4cc3F)c5ccc(F)cc5F

1S/C20H15F3N4O3.CH4O3S/c21-8-1-2-15(13(22)3-8)27-7-12(20(29)30)17(28)9-4-14(23)19(25-18(9)27)26-5-10-11(6-26)16(10)24;1-5(2,3)4/h1-4,7,10-11,16H,5-6,24H2,(H,29,30);1H3,(H,2,3,4)/t10-,11+,16+;

DYNZICQDCVYXFW-AHZSKCOESA-N

5, 25 mg in glass bottle

GHS05,GHS08

Danger

H314 - H361

P201 - P260 - P280 - P301 + P330 + P331 - P303 + P361 + P353 - P305 + P351 + P338

Repr. 2 - Skin Corr. 1B

8B - Non-combustible, corrosive hazardous materials

WGK 3