产品编号：4083738

品牌：Sigma-Aldrich

纯度规格：A cell-permeable inhibitor of SKP2-dependent p27Kip1 ubiquitination. Selectively induces the accumulation SCFSKP2 substrates in multiple myeloma RPMI 8226 cells.

包装规格：10 MG

产品编号：4083737

品牌：Sigma-Aldrich

包装规格：10 MG

产品编号：4083736

品牌：Sigma-Aldrich

纯度规格：A highly potent agonist of GABAB receptor. Shown to be about 10-times more potent than baclofen.

包装规格：10 MG

产品编号：4083734

品牌：Sigma-Aldrich

包装规格：10 MG

产品编号：4083725

品牌：Sigma-Aldrich

纯度规格：A cell-permeable racemic mixture of Halofuginone that inhibits of prolyl-tRNA synthetase.

包装规格：10 MG

产品编号：4083724

品牌：Sigma-Aldrich

纯度规格：A cell-permeable, selective inhibitor of protein arginine methyltransferase 1 (PRMT1; IC₅₀ = 9.5 μM).

包装规格：10 MG

产品编号：4083722

品牌：Sigma-Aldrich

包装规格：10 MG

产品编号：4083721

品牌：Sigma-Aldrich

纯度规格：A cell-permeable inhibitor of Wnt secretion from L-cell Wnt1/2/3/3a/6/7a/9a transfectants (IC₅₀ from 50 pM to 1.1 nM).

包装规格：5 MG

产品编号：4083717

品牌：Sigma-Aldrich

纯度规格：A rhodanine-derived, reversible, photoactivated, TrpA1-selective channel activator.

包装规格：10 MG

产品编号：4083714

品牌：Sigma-Aldrich

纯度规格：A cell-permeable, highly potent and selective inhibitor of phosphodiesterase 5 (PDEV; IC₅₀ = 270 pM).

包装规格：5 MG

产品编号：4083710

品牌：Sigma-Aldrich

纯度规格：A cell-permeable compound that selectively downregulates the expression of p21 (~10 μM), independent of p53.expression, at either transcription or post-transcriptional level.

包装规格：10 MG

产品编号：4083706

品牌：Sigma-Aldrich

纯度规格：A cell-permeable myristoylated hexapeptide that selectively inhibits integrin outside-in signaling without affecting inside-out signaling. Blocks the interaction of Gα3 and integrin β3 subunit.

包装规格：10 MG

产品编号：4083701

品牌：Sigma-Aldrich

纯度规格：A cell-permeable. Reversible, selective inhibitor of the growth of malignant peripheral nerve sheath tumors (EC₅₀ = 439 nM, 754 nM, and 1.0 μM in S462, SNF96.2, and sMPNST cells).

包装规格：25 MG

产品编号：4083697

品牌：Sigma-Aldrich

包装规格：10 MG

产品编号：4083692

品牌：Sigma-Aldrich

纯度规格：A cell-permeable, potent, selective, reversible inhibitor of Lysine-Specific Demethylase 1 (LSD1; IC₅₀ = 13 nM; K_i = 31 nM).

包装规格：10 MG

产品编号：4083691

品牌：Sigma-Aldrich

纯度规格：A cell-permeable, both NADH and pyruvate-competitive isoform A-selective LDH inhibitor. Exhibits enhanced anticancer activity under hypoxic conditions.

包装规格：10 MG

产品编号：4083690

品牌：Sigma-Aldrich

纯度规格：A cell-permeable, fast acting, branched polyamine. Induces growth of actin-enriched lamellipodia within minutes without the need for serum cofactors .

包装规格：10 MG

产品编号：4083688

品牌：Sigma-Aldrich

纯度规格：A voltage gated calcium channel gating inhibitor of the dihydropyridine class.

包装规格：10 MG

产品编号：4083686

品牌：Sigma-Aldrich

纯度规格：A substrate competitive inhibitor of insulin-regulated aminopeptidase (IRAP) activity (K_i = 0.48 μM against 25 μM Leu-AMC).

包装规格：10 MG

产品编号：4083685

品牌：Sigma-Aldrich

纯度规格：A 10 mM (5 mg/1.07 ml) sterile-filtered solution of Wnt Antagonist II, IWP-2) in DMSO.

包装规格：5 MG

产品编号：4083683

品牌：Sigma-Aldrich

纯度规格：A 25 mM (5 mg/357 μl) sterile-filtered solution of PPACK, 2HCl in H₂O.

包装规格：5 MG

产品编号：4083680

品牌：Sigma-Aldrich

包装规格：10 MG

产品编号：4083678

品牌：Sigma-Aldrich

纯度规格：A 50 mM sterile-filtered solution of I-BET in DMSO.

包装规格：5 MG

产品编号：4083677

品牌：Sigma-Aldrich

纯度规格：A 25 mM (2 mg/231 μl) sterile-filtered solution of Ginkgolic Acid (15:1) in DMSO.

包装规格：2 MG

产品编号：4083676

品牌：Sigma-Aldrich

包装规格：5 MG

产品编号：4083675

品牌：Sigma-Aldrich

包装规格：2 MG

产品编号：4083674

品牌：Sigma-Aldrich

纯度规格：A 25 mM solution of (+)-Brefeldin A in DMSO.

包装规格：2 MG

产品编号：4083672

品牌：Sigma-Aldrich

纯度规格：A cell-permeable compound that competitively binds to Hu antigen R (HuR; K_i = 350 nM) and disrupts the interaction of HuR and adenine- and uridine-rich element (ARE) of target mRNAs.

包装规格：10 MG

产品编号：4083670

品牌：Sigma-Aldrich

包装规格：10 MG

产品编号：4083667

品牌：Sigma-Aldrich

纯度规格：Cell-permeable inhibitor of gp130. Binds to gp130 and induces its phosphorylation at Ser782 in ovarian cancer cells. Suppresses constitutive phosphorylation of and nuclear translocation of Stat3.

包装规格：10 MG

产品编号：4083664

品牌：Sigma-Aldrich

产品编号：4083662

品牌：Sigma-Aldrich

纯度规格：Specifically binds to the Fn14 surface (Kd = 7.12 mM) and suppresses TWEAK-induced glioma cell migration.

包装规格：10 MG

产品编号：4083661

品牌：Sigma-Aldrich

纯度规格：A cell-permeable structural analog of E1 that acts as an equipotent, SAM-competitive inhibitor of Ezh2/PRC2 inhibitor (K_i = 0.5 to 3 nM against wt &mutant Ezh2-containing PRC2).

包装规格：5 MG

产品编号：4083658

品牌：Sigma-Aldrich

包装规格：10 MG

产品编号：4083655

品牌：Sigma-Aldrich

纯度规格：DHODH Inhibitor, DSM1, is a highly potent, competitive, tight-binding inhibitor of Plasmodium falciparum dihydroorotate dehydrogenase (IC₅₀ = 47 nM; K_i = 15 nM).

包装规格：25 MG

产品编号：4083653

品牌：Sigma-Aldrich

包装规格：5 MG

产品编号：4083650

品牌：Sigma-Aldrich

包装规格：10 MG

产品编号：4083649

品牌：Sigma-Aldrich

包装规格：10 MG

产品编号：4083648

品牌：Sigma-Aldrich

纯度规格：A 25 mM (10 mg/608 μL) sterile-filtered solution of CMP-Sialic Acid, Disodium Salt in H₂O.

包装规格：10 MG

产品编号：4083647

品牌：Sigma-Aldrich

包装规格：25 MG

产品编号：4083645

品牌：Sigma-Aldrich

纯度规格：A cell-permeable, highly potent, and specific inhibitor of CDC-like kinase (CLK; IC₅₀ = 1.1 and 2.4 nM for CLK1 and CLK2, respectively).

包装规格：5 MG

产品编号：4083644

品牌：Sigma-Aldrich

纯度规格：A cell-permeable, potent, irreversible, non-substrate competitive inhibitor of CD45/PTPRC tyrosine phosphatase activity (IC₅₀ = 290 nM).

包装规格：10 MG

产品编号：4083642

品牌：Sigma-Aldrich

纯度规格：Enhances BMP-2 associated signaling by inhibiting Smurf1-mediated Smad1/5 ubiquitination and thereby prolonging the half-life of Smad1 and 5. in 48 h).

包装规格：10 MG

产品编号：4083641

品牌：Sigma-Aldrich

纯度规格：A cell-permeable compound that downregulates cellular BMI-1 levels by inhibiting BMI-1 transcription.

包装规格：10 MG

产品编号：4083640

品牌：Sigma-Aldrich

纯度规格：A cell permeable, highly potent, selective inhibitor of Aurora A (IC₅₀ = 48 nM). Disrupts MYCN-Aurora A complex.

包装规格：10 MG

产品编号：4083638

品牌：Sigma-Aldrich

纯度规格：A cell-permeable compound that directly and reversibly interacts with miRNA binding domain of Argonaute-2 (K_d = 126 μM) and inhibits binding of miR-20a, miR-26a, miR-107, miR-223 &let-7a to Ago2.

包装规格：25 MG

产品编号：4083634

品牌：Sigma-Aldrich

纯度规格：Acid Ceramidase Inhibitor, BOC, CAS 1644158-57-5, is a cell-permeable, potent inhibitor of acid ceramidase (IC₅₀ = 79 nM against HEK293 lysosomal lysate AC activity).

包装规格：10 MG

产品编号：4083632

品牌：Sigma-Aldrich

纯度规格：An anti-bacterial compound that targets NAD(P)H-dependent enoyl acyl carrier protein reductase (ENR) resulting in the inhibition of bacterial fatty acid synthase.

包装规格：10 MG

产品编号：4083627

品牌：Sigma-Aldrich

纯度规格：A cell-permeable, selective, potent, and reversible inhibitor of USP1-UAF1 deubiquitinase (IC₅₀ = 76 nM in Ub-Rhodamine based assays). Does not disrupt USP1-UAF1 association.

包装规格：10 MG

产品编号：4083625

品牌：Sigma-Aldrich

纯度规格：Directly and selectively binds to the troponin complex in fast skeletal muscle (Kd = 40 nM) and sensitizes it to calcium.

包装规格：10 MG