产品编号：4083622

品牌：Sigma-Aldrich

纯度规格：A potent agonist of Toll-like receptor 8 agonist (TLR8, EC₅₀ = 200 nM).

包装规格：10 MG

产品编号：4083621

品牌：Sigma-Aldrich

包装规格：10 MG

产品编号：4083618

品牌：Millipore

纯度规格：A cell-permeable compound that prevents the transfer of SUMO from the E2 thioester to the substrate without affecting SUMO-activating enzyme E1 (SAE-1/2) or E2 Ubc9-SUMO thioester formation.

包装规格：10 MG

产品编号：4083617

品牌：Sigma-Aldrich

包装规格：5 MG

产品编号：4083616

品牌：Sigma-Aldrich

包装规格：250 μG

产品编号：4083615

品牌：Sigma-Aldrich

纯度规格：A cell-permeable BP-1-102 analog that targets STAT3 and STAT5 with comparable affinity.

包装规格：10 MG

产品编号：4083613

品牌：Sigma-Aldrich

纯度规格：A depolymerized vanadate prepared from Sodium Orthovanadate with enhanced ability to competitively inhibit endogenous phosphatases.

包装规格：5 ML，1 SET

产品编号：4083611

品牌：Sigma-Aldrich

纯度规格：A cell-permeable compound that targets human Replication Protein A (RPA) and inhibits its DNA-binding activity (IC₅₀= 12.9 μM).

包装规格：25 MG

产品编号：4083609

品牌：Sigma-Aldrich

纯度规格：A cell-permeable, selective inhibitor of RIP3-selective kinase with >1,000-fold selectivity over a vast majority of more than 300 other kinases.

包装规格：10 MG

产品编号：4083606

品牌：Sigma-Aldrich

纯度规格：A cell-permeable pharmacological chaperone to increase neuronal retromer levels. Improves Vps35-Vps29-Vps26 retromer complex stability.

包装规格：25 MG

产品编号：4083600

品牌：Sigma-Aldrich

包装规格：10 MG

产品编号：4083599

品牌：Sigma-Aldrich

纯度规格：A cell permeable, brain permeant antagonist of polypeptide chemokine prokineticin 2 receptor (IC₅₀ = 5 nM and 8.2 nM for PKR1 and PKR2, respectively).

包装规格：5 MG

产品编号：4083597

品牌：Sigma-Aldrich

包装规格：2 MG

产品编号：4083596

品牌：Sigma-Aldrich

纯度规格：A cell permeable competitive inhibitor of Pin1 (EC₅₀ = 4.1 μM, K_i = 50 nM).

包装规格：10 MG

产品编号：4083594

品牌：Sigma-Aldrich

纯度规格：A cell-permeable, potent and competitive inhibitor of fructose-2,6-bisphosphatase 3 (PFKFB3; IC₅₀ = 670 nM).

包装规格：25 MG

产品编号：4083593

品牌：Sigma-Aldrich

纯度规格：A cell-permeable inhibitor of PFKFB3 that reversibly docks to its substrate binding domain (IC₅₀ = 207 nM)

包装规格：25 MG

产品编号：4083592

品牌：Sigma-Aldrich

纯度规格：A cell-permeable nematicidal compound that covalently binds to the peroxidatic cysteine of peroxiredoxin II in T. gondii and irreversibly blocks its hyperperoxidation activity (IC₅₀ = 23 μM).

包装规格：25 MG

产品编号：4083589

品牌：Sigma-Aldrich

纯度规格：A cell-permeable, selective &direct blocker of p18-Cdk6 interaction. Inhibits p18INK4C protein activity &favors HSCs self-renewal by ~4.2-fold.

包装规格：25 MG

产品编号：4083588

品牌：Sigma-Aldrich

纯度规格：A cell-permeable compound with cytotoxicity towards quiescent cells in colon cancer 3-D microtissues (~ 6 μM). Reduces mitochondrial oxidative phosphorylation in tumor cells.

包装规格：10 MG

产品编号：4083587

品牌：Sigma-Aldrich

纯度规格：Prevents melanopsin/Opn4 photoactivation in a reversible manner. Inhibits cellular phototransduction mediated by human Opn4 (IC₅₀ = 665 nM; using CHO transfectants).

包装规格：10 MG

产品编号：4083585

品牌：Sigma-Aldrich

包装规格：10 MG

产品编号：4083584

品牌：Sigma-Aldrich

纯度规格：A potent activator of Ca2+ -activated K+ channels of SK and IK types, but not BK type channels. It is at least 1000 times more potent than 1-EBIO.

包装规格：10 MG

产品编号：4083583

品牌：Sigma-Aldrich

纯度规格：A cell-permeable, potent Nrf-2 activator that stimulates HO-1 expression in murine microglial BV-2 cultures. Induces overall Nrf2 cellular accumulation and nuclear translocation.

包装规格：10 MG

产品编号：4083582

品牌：Sigma-Aldrich

纯度规格：A cell-permeable inhibitor of nonsense-mediated mRNA decay (NMD) that enhances the stability of premature termination codon mutated p53 mRNA in N417 and HDQP-1 cells.

包装规格：10 MG

产品编号：4083581

品牌：Sigma-Aldrich

纯度规格：A cell-potent, bioavailable NLRP3 inflammasome activation inhibitor. Effectively blocks caspase-1 &-11 activation, IL-1β processing and IL-1β &IL-6 secretion.

包装规格：10 MG

产品编号：4083578

品牌：Sigma-Aldrich

包装规格：25 MG

产品编号：4083577

品牌：Sigma-Aldrich

纯度规格：A cell-permeable neomycin derived artificial nucleobase conjugate. Inhibits the production of oncogenic miRNAs 372 (IC₅₀ = 2.4 μM) by binding to pre-miRNAs and interrupts processing by Dicer.

包装规格：2 MG

产品编号：4083576

品牌：Sigma-Aldrich

纯度规格：A blood-brain barrier permeable, potent, selective, and reversible antagonist of mGlu7 receptor (IC₅₀ = 3.5 and 2.8 μM for mGlu7a and mGlu7b in CHO cells).

包装规格：10 MG

产品编号：4083575

品牌：Sigma-Aldrich

纯度规格：A cell-permeable, bioavailable, highly potent inhibitor of acyl CoA:monoacylglycerol acyltransferase 2 inhibitor (MGAT2, IC₅₀ = 3.4 nM). Displays good microsomal stability.

包装规格：5 MG

产品编号：4083573

品牌：Sigma-Aldrich

包装规格：10 MG

产品编号：4083571

品牌：Sigma-Aldrich

纯度规格：A synthetic cyclic alkylaminoluciferin with properties superior to D-luciferin. Binds to luciferase with higher affinity.

包装规格：10 MG

产品编号：4083570

品牌：Sigma-Aldrich

纯度规格：A cell-permeable stain for neutral lipids. Does not stain phospholipids.

包装规格：5 MG

产品编号：4083569

品牌：Sigma-Aldrich

包装规格：5 MG

产品编号：4083567

品牌：Sigma-Aldrich

纯度规格：A cell-permeable compound that prevents various bacterial toxins from exerting their cytotoxic activity by blocking endosomal trafficking/maturation into acidified late endosomes.

包装规格：25 MG

产品编号：4083565

品牌：Sigma-Aldrich

纯度规格：A fast acting, reversible, and selective activator of Kir6.2/SUR1 channels (EC₅₀ = 7 μM).

包装规格：10 MG

产品编号：4083563

品牌：Sigma-Aldrich

纯度规格：A cell-permeable, direct, non-covalent inhibitor of Keap1-Nrf2 protein-protein interaction (Kd = 1 μM) that causes the dissociation of Nrf2 from keap1 in the cytosol.

包装规格：10 MG

产品编号：4083562

品牌：Sigma-Aldrich

包装规格：10 MG

产品编号：4083561

品牌：Sigma-Aldrich

包装规格：5 MG

产品编号：4083560

品牌：Sigma-Aldrich

纯度规格：A cell-permeable, superior inhibitor of Jumonji C domain histone lysine demethylase. About 30 fold more potent than IOX1 (EC₅₀ = 3.8 μM for KDM4A in HeLa cells vs. 100 μM for IOX1).

包装规格：10 MG

产品编号：4083558

品牌：Sigma-Aldrich

纯度规格：A cell permeable analog of curcumin that acts as a specific inhibitor of JAK2 (~ 5 μM) and blocks STAT3 phosphorylation in MDA-MB-231 and PANC-1 cancer cells.

包装规格：25 MG

产品编号：4083557

品牌：Sigma-Aldrich

纯度规格：The cell-permeable, selective inhibitor of eIF2α/eIF2S1 Ser51 phosphorylation-initiated UPR response (~25 to 200 nM) upon ER stress induction.

包装规格：10 MG

产品编号：4083556

品牌：Sigma-Aldrich

纯度规格：InSolution^TM Y-27632, Sterile-Filtered, Cell Culture-Tested, CAS 146986-50-7, is a 10 mM sterile-filtered solution of Y-27632 in H₂O. Acts as an inhibitor of Rho kinases (Ki = 140 nM for p160ROCK).

包装规格：2 MG

产品编号：4083555

品牌：Sigma-Aldrich

纯度规格：A 25 mM (2 mg/221 μL) sterile-filtered solution of TLR4 Inhibitor, TAK-242 in DMSO.

包装规格：2 MG

产品编号：4083553

品牌：Sigma-Aldrich

纯度规格：A 25 mM (10 mg/650 μl) sterile-filtered solution of SRT1720, HCl in DMSO.

包装规格：10 MG

产品编号：4083552

品牌：Sigma-Aldrich

纯度规格：A 25 μM (10 mg/583 μL) sterile-filtered solution of Pepstatin A, Synthetic in DMSO.

包装规格：10 MG

产品编号：4083551

品牌：Sigma-Aldrich

包装规格：500 μG

产品编号：4083550

品牌：Sigma-Aldrich

包装规格：5 MG

产品编号：4083549

品牌：Sigma-Aldrich

纯度规格：A 25 mM (1 mg/98 μL) sterile-filtered solution of Histone Methyltransferase EZH2 Inhibitor, DZNep in H₂O.

包装规格：1 MG

产品编号：4083547

品牌：Sigma-Aldrich

纯度规格：A 50 mM (2 mg/106.23 μL) sterile-filtered solution of APT1 Inhibitor, palmostatin B in DMSO.

包装规格：2 MG

产品编号：4083546

品牌：Sigma-Aldrich

纯度规格：A 30 mM (1 mg/98 μL) sterile-filtered solution of Aphidicolin in DMSO.

包装规格：1 MG